To stay on top of its field, it is of utmost importance for Corticalis to always have access to the relevant competencies and skills required.
Therefore, Corticalis have created a strong team of highly skilled and motivated researchers in the relevant areas. All team members are either PhDs or PhD candidates and have shown great innovation and a strong understanding of biomaterials and implantology. Corticalis are currently working with a team consisting of 6 team members in addition to Prof. Ellingsen and Prof. Lyngstadaas.
Corticalis is focused on the continued development of its totally owned, new technologies, NuBone, NuPep and NuGel.
Corticalis main goal is to create optimal bone regeneration. To achieve this, the company develops products that enable bone regeneration from both a biological as well as a 3D structural, mechanical guided bone regeneration (hereinafter referred to as 3D-GBR) approach.
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Conditions such as trauma, tumors, cancer, periodontitis and osteoporosis may lead to bone loss, reduced bone growth and bone volume.
For these and other reasons, it is of great importance to find methods to improve bone growth and to regain bone anatomy. Scaffolds may be used as a framework for the cells participating in the bone regeneration process, but also as a framework as a substitute for the lost bone structure.
Skeletal formation occurs by a process of matrix mediated biomineraliziation in which intracellular and extracellular organic proteins regulate the initiation, growth and deposition of mineral crystals. Among the extracellular proteins that regulate biomineralisation are several molecules that exhibit proline-rich regions, like collagens, amelogenins, ameloblastin and sialoproteins.